Article
Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1.
Current biology : CB - 1 Jan 1998
Cohen N R, Taylor J S, Scott L B, Guillery R W, Soriano P, Furley A J
Abstract excerpt
BACKGROUND: Neural cell adhesion molecules of the immunoglobulin superfamily (IgCAMs) have been implicated in both the fasciculation and guidance of axons, but direct genetic evidence of a role for neural IgCAMs in axon guidance in vertebrates is lacking. The L1 subfamily of vertebrate neural IgCAMs function as both homophilic and heterophilic receptors for a variety of cell-surface and extracellular ligands and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.