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Article

Estimating the parameters of background selection and selective sweeps in Drosophila in the presence of gene conversion.

Proceedings of the National Academy of Sciences of the United States of America - 13 Jun 2017

Campos José Luis, Zhao Lei, Charlesworth Brian

Abstract excerpt

We used whole-genome resequencing data from a population of Drosophila melanogaster to investigate the causes of the negative correlation between the within-population synonymous nucleotide site diversity (πS ) of a gene and its degree of divergence from related species at nonsynonymous nucleotide sites (KA ). By using the estimated distributions of mutational effects on fitness at nonsynonymous and UTR sites, we...

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Identifiers

PMID: 28559322
DOI: 10.1073/pnas.1619434114
PMCID: PMC5474792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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