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Article

Mice with genetically altered glutamate receptors as models of schizophrenia: a comprehensive review.

Neuroscience and biobehavioral reviews - 1 Mar 2010

Inta Dragos, Monyer Hannah, Sprengel Rolf, Meyer-Lindenberg Andreas, Gass Peter

Abstract excerpt

Recent clinical evidence for the effectiveness of new antipsychotic drugs that specifically target glutamate receptors has rekindled interest in the glutamatergic system regarding pathophysiology and treatment of schizophrenia. The glutamatergic hypothesis of schizophrenia was triggered by the clinical/behavioural observation that NMDA receptor antagonists can induce psychosis in humans and abnormal behaviour...

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PMID: 19651155
DOI: 10.1016/j.neubiorev.2009.07.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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