Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of handling on the behavioural phenotype of the neuregulin 1 type III transgenic mouse model for schizophrenia.

Behavioural brain research - 7 May 2021

Guerra Stefan, Chesworth Rose, Weickert Cynthia Shannon, Karl Tim

Abstract excerpt

Handling of laboratory mice affects animal wellbeing and behavioural test outcomes. However, present research has focused on handling effects in common strains of laboratory mice despite the knowledge that environmental factors can modify established phenotypes of genetic mouse models. Thus, we examined the impact of handling on the face validity of a transgenic mouse model for the schizophrenia risk gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anxiety
Share to Behavior, Animal
Share to Cognitive Dysfunction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Neuregulin-1

Share to Reflex, Startle

Share to Schizophrenia

Share to Sex Factors

Source

Identifiers

PMID: 33588020
DOI: 10.1016/j.bbr.2021.113166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of handling on the behavioural phenotype of the neuregulin 1 type III transgenic mouse model for schizophrenia.PMID 33588020Read ↗

Behavioral profile of a heterozygous mutant mouse model for EGF-like domain neuregulin 1.Semantic proximity Read ↗

Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia.Semantic proximity Read ↗

Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous 'knockout' of the schizophrenia risk gene neuregulin-1.Semantic proximity Read ↗

Disruption of the neuregulin 1 gene in the rat alters HPA axis activity and behavioral responses to environmental stimuli.Semantic proximity Read ↗

Do individually ventilated cage systems generate a problem for genetic mouse model research?Semantic proximity Read ↗

Cognitive, emotional and social phenotyping of mice in an observer-independent setting.Semantic proximity Read ↗

Phenotypic characterization of transgenic mice overexpressing neuregulin-1.Semantic proximity Read ↗

Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: a putative model of gene × environment interaction.Semantic proximity Read ↗

Parent-of-origin effects on schizophrenia-relevant behaviours of type III neuregulin 1 mutant mice.Semantic proximity Read ↗

Sex-specific neuroendocrine and behavioral phenotypes in hypomorphic Type II Neuregulin 1 rats.Semantic proximity Read ↗

Cognition in transmembrane domain neuregulin 1 mutant mice.Semantic proximity Read ↗

Characterization of gene-environment interactions by behavioral profiling of selectively bred rats: the effect of NMDA receptor inhibition and social isolation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.