Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimating linkage disequilibrium from genotypes under Hardy-Weinberg equilibrium.

BMC genetics - 26 Feb 2020

Hui Tin-Yu J, Burt Austin

Abstract excerpt

BACKGROUND: Measures of linkage disequilibrium (LD) play a key role in a wide range of applications from disease association to demographic history estimation. The true population LD cannot be measured directly and instead can only be inferred from genetic samples, which are unavoidably subject to measurement error. Previous studies of r2 (a measure of LD), such as the bias due to finite sample size and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Gene Frequency
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Haplotypes

Share to Likelihood Functions

Share to Linkage Disequilibrium

Share to Sample Size

Source

Open in PubMed Open full text

Identifiers

PMID: 32102657
DOI: 10.1186/s12863-020-0818-9
PMCID: PMC7045472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimating linkage disequilibrium from genotypes under Hardy-Weinberg equilibrium.PMID 32102657Read ↗

A tutorial on statistical methods for population association studies.Semantic proximity Read ↗

A likelihood ratio test of population Hardy-Weinberg equilibrium for case-control studies.Semantic proximity Read ↗

Distributions of Hardy-Weinberg equilibrium test statistics.Semantic proximity Read ↗

Estimating Disequilibrium Coefficients.Semantic proximity Read ↗

Adapting the logical basis of tests for Hardy-Weinberg Equilibrium to the real needs of association studies in human and medical genetics.Semantic proximity Read ↗

Detecting genome-wide haplotype polymorphism by combined use of Mendelian constraints and local population structure.Semantic proximity Read ↗

Comparison of estimators for measures of linkage disequilibrium.Semantic proximity Read ↗

Estimating disequilibrium coefficients.Semantic proximity Read ↗

Linkage effects and analysis of finite sample errors in the HapMap.Semantic proximity Read ↗

A note on exact tests of Hardy-Weinberg equilibrium.Semantic proximity Read ↗

Allele frequencies and the r2 measure of linkage disequilibrium: impact on design and interpretation of association studies.Semantic proximity Read ↗

Testing Hardy-Weinberg disequilibrium using the generalized linear model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.