A Leu184Val polymorphism in PCK1 gene is associated with type 2 diabetes in Eastern Chinese population with BMI<23 kg/m2.

doi:10.1016/j.diabres.2008.10.011

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Article

A Leu184Val polymorphism in PCK1 gene is associated with type 2 diabetes in Eastern Chinese population with BMI<23 kg/m2.

Diabetes research and clinical practice - 1 Feb 2009

Dong Yan, Zhang Hongli, Wang Xiao, Feng Qiwen, Chen Xueru, Su Qing

Abstract excerpt

Our previous finding has shown that a suggestive linkage existed in D20S196 in diabetic families with lowered BMI in eastern Chinese population. The aim of this study is to investigate whether variants in PCK1 gene, located in this region, was associated with type 2 diabetes in eastern China. Eleven SNPs were identified by sequencing in PCK1. The G (Val184) allele of rs707555 (Leu184Val) in diabetic group was...

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PMID: 19070910
DOI: 10.1016/j.diabres.2008.10.011

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PCK1

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