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Article

Association of pyruvate dehydrogenase kinase 4 gene polymorphisms with type 2 diabetes and metabolic syndrome.

Diabetes research and clinical practice - 1 Feb 2012

Moon Seong-Su, Lee Jung-Eun, Lee Young-Sil, Kim Su-Won, Jeoung Nam Ho, Lee In-Kyu, Kim Jung-Guk

Abstract excerpt

AIMS: Pyruvate dehydrogenase kinase 4 (PDK4) plays a crucial role in glucose utilization and lipid metabolism by regulating the pyruvate dehydrogenase complex (PDC) and is an emerging therapeutic target for type 2 diabetes. To date, no study has specifically examined the relationship between PDK4 gene polymorphisms and type 2 diabetes or metabolic syndrome. METHODS: The association of common single nucleotide...

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Source

Identifiers

PMID: 22019269
DOI: 10.1016/j.diabres.2011.09.035

Genes

PDK4
PDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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