Article
The E23K variation in the KCNJ11 gene is associated with type 2 diabetes in Chinese and East Asian population.
Journal of human genetics - 1 Jul 2009
Zhou Daizhan, Zhang Di, Liu Yun, Zhao Teng, Chen Zhuo, Liu Zhe, Yu Lan, Zhang Zuofeng, Xu He, He Lin
Abstract excerpt
The genes (ABCC8 and KCNJ11) have a key role in glucose-stimulated insulin secretion and thus have always been considered as excellent susceptibility candidates for involvement in type 2 diabetes. Common polymorphisms (KCNJ11 E23K and ABCC8 exon16-3t/c) in these genes have been reported to be associated with type 2 diabetes in various European-descent populations. However, there were inconsistent results in...
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