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Article

Rs2227982 and rs2227981 in PDCD1 gene are functional SNPs associated with T1D risk in East Asian.

Acta diabetologica - 1 Aug 2018

Gu Yong, Xiao Lei, Gu Wei, Chen Shu, Feng Yingjie, Wang Jian, Wang Zhixiao, Cai Yun, Chen Heng, Xu Xinyu, Shi Yun, Zhang Mei, Xu Kuanfeng, Yang Tao

Abstract excerpt

AIMS: To investigate whether PDCD1 gene polymorphisms are functional, and their associations with T1D risk and related clinical characteristics. METHODS: A total of 3060 Chinese Han individuals (1019 T1D patients and 2041 healthy controls) were genotyped for 4 tag single nucleotide polymorphisms (SNPs) within the PDCD1 region (rs2227982, rs7421861, rs10204525, and rs6710479) and another most studied synonymous...

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Source

Identifiers

PMID: 29774466
DOI: 10.1007/s00592-018-1152-9

Genes

PDCD1

Variants

Rs2227982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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