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Article

Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus.

The Journal of clinical endocrinology and metabolism - 1 Feb 2004

Cao Henian, van der Veer Eric, Ban Matthew R, Hanley Anthony J G, Zinman Bernard, Harris Stewart B, Young T Kue, Pickering J Geoffrey, Hegele Robert A

Abstract excerpt

We sequenced the promoter and coding regions of PCK1 encoding cytosolic phosphoenolpyruvate carboxykinase from genomic DNA of subjects with type 2 diabetes mellitus (DM). We found nine single nucleotide polymorphisms (SNPs) that were present with varying allele frequencies and pairwise linkage disequilibrium relationships in different ethnic groups. The -232C-->G promoter SNP was within a cis-acting element...

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Identifiers

PMID: 14764811
DOI: 10.1210/jc.2003-031361

Genes

PCK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus.PMID 14764811Read ↗

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