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Article

Genetic control of susceptibility to diethylnitrosamine and dimethylbenzanthracene carcinogenesis in rats.

The American journal of pathology - 1 Jul 1991

Melhem M F, Kunz H W, Gill T J

Abstract excerpt

The susceptibility to cancer induction after a single dose of diethylnitrosamine in male rats and a single dose of dimethylbenzanthracene in female rats was examined in the grc- strain R16 and the grc+ strain ACP, both of which have the same major histocompatibility complex genes but differ in the grc region. No tumor-promoting regimens were used, and the animals were fed only laboratory chou. The R16 males...

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Identifiers

PMID: 1906684
PMCID: PMC1886134

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