Genetic regulation of mammary carcinogenesis in the rat by susceptibility and suppressor genes.

doi:10.1289/ehp.9193161

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Article

Genetic regulation of mammary carcinogenesis in the rat by susceptibility and suppressor genes.

Environmental health perspectives - 1 Jun 1991

Gould M N, Zhang R

Abstract excerpt

Rat strains differ in their susceptibilities to mammary carcinogenesis. Strains such as Wistar-Furth are very susceptible to chemically induced carcinogenesis. This phenotype is controlled by autosomally dominant susceptibility genes. Strains such as the Copenhagen are resistant to spontaneous and induced mammary carcinogenesis. This phenotype is controlled by an autosomal dominant gene termed the mammary...

Topics

9,10-Dimethyl-1,2-benzanthracene
Adenoma
Animals
Carcinoma
Cell Differentiation
Chimera
Crosses, Genetic
DNA Damage
Epithelium
Female
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Tumor Suppressor

Genetic Predisposition to Disease

Graft Survival

Mammary Glands, Animal

Mammary Neoplasms, Experimental

Neoplasm Transplantation

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 1773787
DOI: 10.1289/ehp.9193161
PMCID: PMC1568057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1773787-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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