Article
Differences in gene expression and benzo[a]pyrene-induced DNA adduct formation in the liver of three strains of female mice with identical AhRb2 genotype treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin and/or benzo[a]pyrene.
Journal of applied toxicology : JAT - 1 Aug 2008
Wu Qing, Suzuki Junko S, Zaha Hiroko, Lin Tien-Min, Peterson Richard E, Tohyama Chiharu, Ohsako Seiichiroh
Abstract excerpt
To search for genes whose products modify aryl hydrocarbon receptor (AhR)-dependent toxicity caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), gene expression profiles in the liver were surveyed using microarrays 24 h after the administration of TCDD to three strains of female mice, BALB/cAnN...
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