Article
Tumor necrosis factor gene variation and the risk of mortality after burn injury: a cohort study.
Journal of burn care & research : official publication of the American Burn Association - 1 Jan 2000
Shalhub Sherene, Pham Tam N, Gibran Nicole S, O'keefe Grant E
Abstract excerpt
Infection risk and mortality after burn trauma are primarily determined by patient age, burn size and depth, and associated inhalation injury. Whether genetic differences contribute to otherwise unexpected variability in outcomes is unknown. We sought to determine whether there was an association between genetic variation in inflammation-related genes and outcomes after burn trauma. We evaluated patients with...
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