Article
Analysis of IL-6, IL-10 and IL-17 genetic polymorphisms as risk factors for sepsis development in burned patients.
Burns : journal of the International Society for Burn Injuries - 1 Mar 2012
Accardo Palumbo A, Forte G I, Pileri D, Vaccarino L, Conte F, D'Amelio L, Palmeri M, Triolo A, D'Arpa N, Scola L, Misiano G, Milano S, Lio D
Abstract excerpt
Infection risk, sepsis and mortality after severe burn are primarily determined by patient age, burn size, and depth. Whether genetic differences contribute to otherwise unexpected variability in outcomes is unknown. We sought to determine whether there was an association between IL-6, IL-10 and IL-17 polymorphisms with cytokine production and development of sepsis. We evaluated 71 patients with burns ≥15% TBSA...
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