Article
IL-10 polymorphism associated with decreased risk for mortality after burn injury.
The Journal of surgical research - 1 Nov 2010
Huebinger Ryan M, Rivera-Chavez Fernando, Chang Ling-Yu, Liu Ming-Mei, Minei Joseph P, Purdue Gary F, Hunt John L, Arnoldo Brett D, Barber Robert C
Abstract excerpt
OBJECTIVE: Evaluation of single nucleotide polymorphisms (SNPs) in the interleukin-10 promoter (-592 and -819) on risk for death after burn injury. METHODS: Association between the IL-10 SNPs and outcome after burn injury was evaluated in a cohort of 265 patients from Parkland Hospital, Dallas, TX with ≥ 15% TBSA burns without non-burn trauma (ISS ≤ 16), traumatic or anoxic brain injury or spinal cord injury, who...
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