Article
Relationships between common polymorphisms of adenosine triphosphate-binding cassette transporter A1 and high-density lipoprotein cholesterol and coronary heart disease in a population with type 2 diabetes mellitus.
Metabolism: clinical and experimental - 1 Jan 2009
Porchay-Baldérelli Isabelle, Péan Franck, Emery Nathalie, Maimaitiming Suliya, Bellili Naima, Travert Florence, Mohammedi Kamel, Roussel Ronan, Marre Michel, Fumeron Frédéric
Abstract excerpt
Patients with type 2 diabetes mellitus (T2D) have a high coronary risk partly because of low levels of high-density lipoprotein-cholesterol (HDL-C). The adenosine triphosphate-binding cassette transporter A1 (ABCA1) plays a key role in HDL metabolism. We studied the association of common single nucleotide polymorphisms (SNPs) in the ABCA1 gene with HDL-C levels and coronary risk in a cohort of subjects with T2D....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.