Article
ABCA1 C69T gene polymorphism and risk of type 2 diabetes mellitus in a Saudi population.
Journal of biosciences - 1 Dec 2013
Alharbi Khalid K, Khan Imran Ali, Al-Daghri Nasser M, Munshi Anjana, Sharma Vandana, Mohammed Abdul Khader, Wani Kaiser A, Al-Sheikh Yazeed A, Al-Nbaheen May Salem, Ansari Mohammed Ghouse Ahmed, Syed Rabbani
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a disease induced by complex interactions between environmental factors and certain genetic factors. Genetic variants in the Adenosine Binding Cassette Transporter Proteins 1 (ABCA1) have been associated with abnormalities of serum lipid levels of high-density lipoprotein (HDL-C). Decreased serum levels of HDL-C have often been observed in T2DM cases, and this condition has been...
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