Article
Common gene polymorphism in ATP-binding cassette transporter A1 and coronary artery disease: A genetic association study and a structural analysis.
Journal of cellular biochemistry - 1 Jun 2020
Karimian Mohammad, Momeni Ali, Farmohammadi Amir, Behjati Mohaddeseh, Jafari Marjan, Raygan Fariba
Abstract excerpt
ATP-binding cassette transporter A1 (ABCA1) has a crucial role in removing intracellular cholesterol and plays a protective role against atherosclerosis. Therefore, genetic polymorphisms in this gene may alter the susceptibility to coronary artery disease (CAD). This study was aimed to examine the association of rs2230806 (c.1051 G > A; p.R219K) variation in the ABCA1 gene with CAD in a case-control design which...
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