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Article

High quality structure of cleaved PAI-1-stab.

Journal of structural biology - 1 Feb 2009

Dewilde M, Strelkov S V, Rabijns A, Declerck P J

Abstract excerpt

Here we report the crystal structure of a stablilized plasminogen activator inhibitor-1 variant (PAI-1-N150H-K154T-Q301P-Q319L-M354I (PAI-1-stab)) that shows a cleavage within the reactive centre loop. The new structure is of superior quality compared to the previously determined structure of the cleaved PAI-1-A335P mutant. We present a detailed comparison of the two structures and also compare them with the...

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Source

Identifiers

PMID: 19059484
DOI: 10.1016/j.jsb.2008.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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