Article
High quality structure of cleaved PAI-1-stab.
Journal of structural biology - 1 Feb 2009
Dewilde M, Strelkov S V, Rabijns A, Declerck P J
Abstract excerpt
Here we report the crystal structure of a stablilized plasminogen activator inhibitor-1 variant (PAI-1-N150H-K154T-Q301P-Q319L-M354I (PAI-1-stab)) that shows a cleavage within the reactive centre loop. The new structure is of superior quality compared to the previously determined structure of the...
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