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Article

A neuregulin 1 variant is associated with increased lateral ventricle volume in patients with first-episode schizophrenia.

Biological psychiatry - 15 Mar 2009

Mata Ignacio, Perez-Iglesias Rocio, Roiz-Santiañez Roberto, Tordesillas-Gutierrez Diana, Gonzalez-Mandly Andres, Vazquez-Barquero Jose Luis, Crespo-Facorro Benedicto

Abstract excerpt

BACKGROUND: Structural brain abnormalities are already present at early phases of psychosis and might be the consequence of neurodevelopmental deviance. Neuregulin 1 gene (NRG1) is a candidate gene for schizophrenia, and its protein has different roles in nervous system development and plasticity. A single nucleotide polymorphism (SNP) within NRG1, SNP8NRG243177, has been associated with brain function among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19058791
DOI: 10.1016/j.biopsych.2008.10.020

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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