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Article

Basic helix-loop-helix transcription factor NEUROG1 and schizophrenia: effects on illness susceptibility, MRI brain morphometry and cognitive abilities.

Schizophrenia research - 1 Dec 2008

Ho Beng-Choon, Epping Eric, Wang Kai, Andreasen Nancy C, Librant Amy, Wassink Thomas H

Abstract excerpt

Transcription factors, including the basic helix-loop-helix (bHLH) family, regulate numerous genes and play vital roles in controlling gene expression. Consequently, transcription factor mutations can lead to phenotypic pleiotropy, and may be a candidate mechanism underlying the complex genetics and heterogeneous phenotype of schizophrenia. Neurogenin1 (NEUROG1; a.k.a. Ngn1 or Neurod3), a bHLH transcription...

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Identifiers

PMID: 18799289
DOI: 10.1016/j.schres.2008.08.009
PMCID: PMC2597152

Genes

NEUROG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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