Is neuregulin 1 involved in determining cerebral volumes in schizophrenia? Preliminary results showing a decrease in superior temporal gyrus volume.

doi:10.1159/000330584

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Article

Is neuregulin 1 involved in determining cerebral volumes in schizophrenia? Preliminary results showing a decrease in superior temporal gyrus volume.

Neuropsychobiology - 1 Jan 2012

Tosato Sarah, Bellani Marcella, Bonetto Chiara, Ruggeri Mirella, Perlini Cinzia, Lasalvia Antonio, Marinelli Veronica, Rambaldelli Gianluca, Cristofalo Doriana, Bertani Mariaelena, Zanoni Martina, Lazzarotto Lorenza, Cerini Roberto, Pozzi Mucelli Roberto, Tansella Michele, Dazzan Paola, Di Forti Marta, Murray Robin M, Collier David A, Brambilla Paolo

Abstract excerpt

BACKGROUND/AIMS: Reduced left superior temporal gyrus (STG) volume is one of the most replicated imaging findings in schizophrenia. However, it remains unclear whether genes play any role in our understanding of such structural alteration. It has been proposed that Neuregulin 1 (NRG1) might be a promising gene involved in schizophrenia, because of its role in neurodevelopment and neuroplasticity. In this study,...

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PMID: 22378022
DOI: 10.1159/000330584

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NRG1

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