Article
NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis.
Translational psychiatry - 17 Sept 2019
Alliey-Rodriguez Ney, Grey Tamar A, Shafee Rebecca, Asif Huma, Lutz Olivia, Bolo Nicolas R, Padmanabhan Jaya, Tandon Neeraj, Klinger Madeline, Reis Katherine, Spring Jonathan, Coppes Lucas, Zeng Victor, Hegde Rachal R, Hoang Dung T, Bannai Deepthi, Nawaz Uzma, Henson Philip, Liu Siyuan, Gage Diane, McCarroll Steven, Bishop Jeffrey R, Hill Scot, Reilly James L, Lencer Rebekka, Clementz Brett A, Buckley Peter, Glahn David C, Meda Shashwath A, Narayanan Balaji, Pearlson Godfrey, Keshavan Matcheri S, Ivleva Elena I, Tamminga Carol, Sweeney John A, Curtis David, Badner Judith A, Keedy Sarah, Rapoport Judith, Liu Chunyu, Gershon Elliot S
Abstract excerpt
Schizophrenia, Schizoaffective, and Bipolar disorders share behavioral and phenomenological traits, intermediate phenotypes, and some associated genetic loci with pleiotropic effects. Volumetric abnormalities in brain structures are among the intermediate phenotypes consistently reported associated with these disorders. In order to examine the genetic underpinnings of these structural brain modifications, we...
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