Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue.

Development (Cambridge, England) - 1 Jan 2009

Matsuda Miho, Chitnis Ajay B

Abstract excerpt

Mind bomb1 (Mib1)-mediated endocytosis of the Notch ligand DeltaD is essential for activation of Notch in a neighboring cell. Although most DeltaD is localized in cytoplasmic puncta in zebrafish neural tissue, it is on the plasma membrane in mib1 mutants because Mib1-mediated endocytosis determin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Endocytosis
Share to Ligands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurogenesis

Share to Receptors, Notch

Share to Ubiquitin-Protein Ligases

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19056830
DOI: 10.1242/dev.027938
PMCID: PMC2685967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19056830-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue.PMID 19056830Read ↗

Identification of the Mind Bomb1 Interaction Domain in Zebrafish DeltaD.Semantic proximity Read ↗

Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta.Semantic proximity Read ↗

Mind bomb-2 is an E3 ligase for Notch ligand.Semantic proximity Read ↗

Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila.Semantic proximity Read ↗

An obligatory role of mind bomb-1 in notch signaling of mammalian development.Semantic proximity Read ↗

Endocytic internalization routes required for delta/notch signaling.Semantic proximity Read ↗

Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.Semantic proximity Read ↗

Neuralized promotes basal to apical transcytosis of delta in epithelial cells.Semantic proximity Read ↗

The interplay between DSL proteins and ubiquitin ligases in Notch signaling.Semantic proximity Read ↗

Transcriptome analysis of the zebrafish mind bomb mutant.Semantic proximity Read ↗

The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.Semantic proximity Read ↗

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.