Article
Conserved sequence block clustering and flanking inter-cluster flexibility delineate enhancers that regulate nerfin-1 expression during Drosophila CNS development.
Gene expression patterns : GEP - 1 Feb 2009
Kuzin Alexander, Kundu Mukta, Ekatomatis Antonios, Brody Thomas, Odenwald Ward F
Abstract excerpt
We have identified clusters of conserved sequences constituting discrete modular enhancers within the Drosophilanerfin-1 locus. nerfin-1 encodes a Zn-finger transcription factor that directs pioneer interneuron axon guidance. nerfin-1 mRNA is detected in many early delaminating neuroblasts, ganglion mother cells and transiently in nascent neurons. The comparative genomics analysis program EvoPrinter revealed...
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