Article
The genetic polymorphisms of HER-2 and the risk of lung cancer in a Korean population.
BMC cancer - 4 Dec 2008
Jo Uk Hyun, Han Sle Gi Lo, Seo Jae Hong, Park Kyong Hwa, Lee Jae Won, Lee Hyo Jung, Ryu Jeong Seon, Kim Yeul Hong
Abstract excerpt
BACKGROUND: Human Epidermal Growth Factor Receptor 2 (HER-2; also known as erbB-2 or neu), a proto-oncogene of the receptor tyrosine kinase superfamily, has been associated with carcinogenesis and prognosis of human cancers, acting as a binding partner of other epidermal growth factor receptor (EGFR) family in the activation of EGFR signaling. Amplification of the HER-2 gene has been reported in lung cancer,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
