Article
Polymorphisms in the epidermal growth factor receptor gene and the risk of primary lung cancer: a case-control study.
BMC cancer - 24 Oct 2007
Choi Jin Eun, Park Sun Ha, Kim Kyung Mee, Lee Won Kee, Kam Sin, Cha Sung Ick, Kim Chang Ho, Kang Young Mo, Kim Young-Chul, Han Sung Beom, Jung Tae Hoon, Park Jae Yong
Abstract excerpt
BACKGROUND: Polymorphisms in Epidermal Growth Factor Receptor (EGFR) gene may influence EGFR production and/or activity, thereby modulating susceptibility to lung cancer. To test this hypothesis, we investigated the association between polymorphisms in the EGFR gene and the risk of lung cancer in a Korean population. METHODS: We first examined the frequencies of 39 candidate polymorphisms in the EGFR gene in 27...
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