Article
Epidemiological study of HER-2 mutations among EGFR wild-type lung adenocarcinoma patients in China.
BMC cancer - 28 Oct 2016
Li Xuefei, Zhao Chao, Su Chunxia, Ren Shengxiang, Chen Xiaoxia, Zhou Caicun
Abstract excerpt
BACKGROUND: Human epidermal growth factor receptor (HER)-2 is a driver gene in non-small cell lung cancer (NSCLC). The present study evaluated the mutation rate of HER-2 within the wild-type epidermal growth factor receptor (EGFR) lung adenocarcinoma population in China. METHODS: Formalin-fixed, paraffin-embedded samples from 456 patients with wild-type EGFR lung adenocarcinoma were analyzed for HER-2 mutations...
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