Article
HER2 and lung cancer.
Expert review of anticancer therapy - 1 Oct 2013
Landi Lorenza, Cappuzzo Federico
Abstract excerpt
In non-small-cell lung cancer (NSCLC), the identification of oncogenic driver mutations led to the definition of different clinical entities with different therapeutic opportunities, as demonstrated in patients harboring EGF receptor (EGFR) mutations or anaplastic lymphoma kinase translocations. Human EGFR2 (or HER2) has an established role as a prognostic and predictive factor in breast cancer. Although HER2...
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