Article
HER2 mutations in lung adenocarcinomas: A report from the Lung Cancer Mutation Consortium.
Cancer - 1 Nov 2017
Pillai Rathi N, Behera Madhusmita, Berry Lynne D, Rossi Mike R, Kris Mark G, Johnson Bruce E, Bunn Paul A, Ramalingam Suresh S, Khuri Fadlo R
Abstract excerpt
BACKGROUND: Human epidermal growth factor receptor 2 (HER2) mutations have been reported in lung adenocarcinomas. Herein, the authors describe the prevalence, clinical features, and outcomes associated with HER2 mutations in 1007 patients in the Lung Cancer Mutation Consortium (LCMC). METHODS: Patients with advanced-stage lung adenocarcinomas were enrolled to the LCMC. Tumor specimens were assessed for diagnosis...
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