Article
[Current management and future prospect of HER-2 mutant non-small cell lung cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 Oct 2020
Xu F, Wang Y
Abstract excerpt
Since Erb-B2 receptor tyrosine kinase 2 (HER-2) was regarded as oncogenic driver gene for malignancies, HER-2 targeted therapy has benefited many patients with breast cancer and gastric cancer. However, as a member of the epidermal growth factor receptor (EGFR) family, HER-2 has failed to respond well to both traditional anti-HER-2 and anti-EGFR targeted agents when compared to EGFR in non-small cell lung cancer...
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