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Article

Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2009

Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Nishio A, Chiba T

Abstract excerpt

UNLABELLED: BACKGROUND" Human thymic stromal lymphopoietin (TSLP) is expressed in the human asthmatic lung and activates dendritic cells (DCs) to strongly induce proallergic T-helper type 2 (Th2) cell responses, suggesting that TSLP plays a critical role in the pathophysiology of human asthma. Th2 cells are predominantly involved in mild asthma, whereas a mixture of Th1 and Th2 cells with neutrophilic...

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Share to Dendritic Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19055649
DOI: 10.1111/j.1365-2222.2008.03151.x
PMCID: PMC7164823

Genes

TSLP
TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions.PMID 19055649Read ↗

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