Article
Functional plasticity of human respiratory tract dendritic cells: GM-CSF enhances T(H)2 development.
The Journal of allergy and clinical immunology - 1 Nov 2005
Faith Alexander, McDonald Joanne, Peek Emma, Richards David, Caulfield Jason, Chevretton Elfy, Roberts David, Lee Tak, Corrigan Christopher, Hawrylowicz Catherine
Abstract excerpt
BACKGROUND: Dendritic cells within the human respiratory mucosa (RTDCs) are proposed to initiate immune responses to foreign antigens. Their capacity to polarize T-cell responses, however, has not been investigated. OBJECTIVE: To compare RTDCs with peripheral blood dendritic cells (PBDCs) with regard to phenotype, cytokine production, capacity to polarize T-cell responses, and effects of exposure to the...
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