Article
STAM adaptor proteins interact with COPII complexes and function in ER-to-Golgi trafficking.
Traffic (Copenhagen, Denmark) - 1 Feb 2009
Rismanchi Neggy, Puertollano Rosa, Blackstone Craig
Abstract excerpt
Signal-transducing adaptor molecules (STAMs) are involved in growth factor and cytokine signaling as well as receptor degradation, and they form complexes with a number of endocytic proteins, including Hrs and Eps15. In this study, we demonstrate that STAM proteins also localize prominently to early exocytic compartments and profoundly regulate Golgi morphology. Upon STAM overexpression in cells, the Golgi...
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