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Coronavirus M proteins disperse the trans-Golgi network and inhibit anterograde protein trafficking in the secretory pathway

2025-09-08

Abstract excerpt

<h4>ABSTRACT</h4> Coronaviruses (CoVs) encode Spike, Membrane (M), and Envelope (E) transmembrane proteins that are translated and processed at the endoplasmic reticulum (ER) and traverse the secretory pathway to converge at sites of virus assembly. Three transmembrane ER resident proteins, activating transcription factor 6 (ATF6), inositol-requiring enzyme 1 (IRE1), and PKR-like endoplasmic reticulum kinase (PER...

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Literature Corpus work
bd0776ef-3d14-58dc-9efa-164ab1d75ef3
DOI
10.1101/2025.09.05.674545
Open publication

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Coronavirus M proteins disperse the trans-Golgi network and inhibit anterograde protein trafficking in the secretory pathwayDOI 10.1101/2025.09.05.674545
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