Article
Antioxidant small molecules confer variable protection against oxidative damage in yeast mutants.
Journal of agricultural and food chemistry - 24 Dec 2008
Amari Foued, Fettouche Abdelmadjid, Samra Mario Abou, Kefalas Panagiotis, Kampranis Sotirios C, Makris Antonios M
Abstract excerpt
To assess the capacity of small molecules to function as antioxidants in pathologic conditions, a set of yeast assays utilizing strains deficient in the antioxidant machinery was applied with measurements of reactive oxygen species (ROS), glutathione (GSH/GSSG), and induction of the stress responsive proteins oye2 and oye3. Yeast strains deficient in superoxide dismutase (Delta sod1), catalase A (Delta cta1), and...
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