Article
Oxidative damage to proteins in yeast cells exposed to adaptive levels of H(2)O(2).
Redox report : communications in free radical research - 1 Jan 2003
Poljak Anne, Dawes Ian W, Ingelse Benno A, Duncan Mark W, Smythe George A, Grant Chris M
Abstract excerpt
When yeast cells are exposed to sublethal concentrations of oxidants, they adapt to tolerate subsequent lethal treatments. Here, we show that this adaptation involves tolerance of oxidative damage, rather than protection of cellular constituents. o- and m-tyrosine levels are used as a sensitive measure of protein oxidative damage and we show that such damage accumulates in yeast cells exposed to H(2)O(2) at low...
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