Article
Yeast glutathione reductase is required for protection against oxidative stress and is a target gene for yAP-1 transcriptional regulation.
Molecular microbiology - 1 Jul 1996
Grant C M, Collinson L P, Roe J H, Dawes I W
Abstract excerpt
Glutathione (GSH) is an abundant cellular thiol which has been implicated in many cellular processes including protection against xenobiotics, carcinogens and free radicals. Utilization of GSH in both enzymic and non-enzymic defence mechanisms results in its conversion to the oxidized form (GSSG)...
Topics
- Base Sequence
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Glutathione
- Glutathione Disulfide
- Glutathione Reductase
- Hydrogen Peroxide
- Mutation
- Oxidants
- Oxidative Stress
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors