Article
Superoxide radicals have a protective role during H2O2 stress.
Molecular biology of the cell - 1 Sept 2013
Thorpe Geoffrey W, Reodica Mayfebelle, Davies Michael J, Heeren Gino, Jarolim Stefanie, Pillay Bethany, Breitenbach Michael, Higgins Vincent J, Dawes Ian W
Abstract excerpt
Reactive oxygen species (ROS) consist of potentially toxic, partly reduced oxygen species and free radicals. After H(2)O(2) treatment, yeast cells significantly increase superoxide radical production. Respiratory chain complex III and possibly cytochrome b function are essential for this increase. Disruption of complex III renders cells sensitive to H(2)O(2) but not to the superoxide radical generator menadione....
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