Article
Alleles at four HLA class II loci determined by oligonucleotide hybridization and their associations in five ethnic groups.
Immunogenetics - 1 Jan 1991
Fernandez-Viña M A, Gao X J, Moraes M E, Moraes J R, Salatiel I, Miller S, Tsai J, Sun Y P, An J B, Layrisse Z
Abstract excerpt
The use of polymerase chain reaction (PCR) and oligonucleotide hybridization offers a new approach for the definition of HLA class II alleles. It has been possible to determine 43 alleles of DRB1, four of DRB3, two of DRB4, four of DRB5, eight of DQA1, and 14 of DQB1. These alleles are inherited...
Topics
- Alleles
- Asian People
- Base Sequence
- Black People
- DNA Probes
- Gene Frequency
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- Haplotypes
- Hispanic or Latino
- Histocompatibility Antigens Class II
- Humans
- Immunophenotyping