Article
Detection of 14 HLA-DQB1 alleles by oligotyping.
Human immunology - 1 Jun 1991
Molkentin J, Gorski J, Baxter-Lowe L A
Abstract excerpt
Fourteen alleles have been identified by analysis of the nucleotide sequences encoding the HLA-DQB1 chain. This study describes the detection of these 14 alleles by selective gene amplification and sequence-specific hybridization with nonradioactive oligonucleotide probes. These techniques were e...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- DNA
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Histocompatibility Testing
- Humans
- Immunoblotting
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Polymorphism, Genetic