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Article

Molecular diversity of the HLA-C locus in unrelated marrow transplantation.

Tissue antigens - 1 Aug 1994

Petersdorf E W, Stanley J F, Martin P J, Hansen J A

Abstract excerpt

The diversity of HLA-C exon-2 alleles in 56 HLA-A, B, DRB and DQB1-matched patient-unrelated marrow donor pairs was examined by non-cloning polymerase chain reaction-based sequencing of genomic DNA. This method allows simultaneous analysis of both alleles in heterozygous samples. All Cw5-positive individuals encoded a sequence which differed from the published Cw*0501 sequence at position 61. Among 82 samples...

Topics

Alleles
Base Sequence
Bone Marrow Transplantation
Exons
Gene Frequency
Genes, MHC Class I
Genotype
HLA-C Antigens
Histocompatibility Testing
Humans
Molecular Sequence Data
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Genetic

Retrospective Studies

Source

Identifiers

PMID: 7817383
DOI: 10.1111/j.1399-0039.1994.tb02364.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7817383-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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