Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of frequency and phenotype of antigen-specific T cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Stock Angus, Cerundolo Vincenzo

Abstract excerpt

Over the last decade, our understanding of the cellular immune system has been greatly advanced through the development of methods to identify antigen-specific T cells directly ex vivo. The major reagents and techniques used for this purpose are (i) tetramerised MHC:peptide complexes (tetramers) which bind to specific T-cell receptors (TCR) and (ii) assays that detect T cells which synthesise cytokines in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens
Share to Epitopes
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunologic Techniques

Share to Intracellular Space

Share to Lymphocyte Count

Share to Protein Structure, Quaternary

Share to Staining and Labeling

Source

Identifiers

PMID: 19048209
DOI: 10.1007/978-1-60327-527-9_1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of frequency and phenotype of antigen-specific T cells.PMID 19048209Read ↗

Peptide-MHC class I and class II tetramers: From flow to mass cytometry.Semantic proximity Read ↗

Analysis of antigen reactive T-cells.Semantic proximity Read ↗

In Situ MHC-tetramer Staining and Quantitative Analysis to Determine the Location, Abundance, and Phenotype of Antigen-specific CD8 T Cells in Tissues.Semantic proximity Read ↗

High-dimensional analysis of human CD8(+) T cell phenotype, function, and antigen specificity.Semantic proximity Read ↗

Identification of Human Antigen-Specific CD4+ Cells with Peptide-MHC Multimer Technologies.Semantic proximity Read ↗

T‐cell activation–induced marker assays in health and diseaseSemantic proximity Read ↗

Studies of human antiviral CD8+ lymphocytes using class I peptide tetramers.Semantic proximity Read ↗

Flow cytometric analysis of intracellular cytokines: a powerful new tool for the clinical assessment of immune responsiveness.Semantic proximity Read ↗

Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells.Semantic proximity Read ↗

Use of cell-tracking dyes to determine proliferation precursor frequencies of antigen-specific T cells.Semantic proximity Read ↗

Ex vivo analysis of phenotype and TCR usage in relation to CD45 isoform expression on cytomegalovirus-specific CD8+ T lymphocytes.Semantic proximity Read ↗

Frequency and reactivity of antigen-specific T cells were concurrently measured through the combination of artificial antigen-presenting cell, MACS and ELISPOT.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.