Article
Studies of human antiviral CD8+ lymphocytes using class I peptide tetramers.
Reviews in medical virology - 1 Jan 2000
Lechner F, Cuero A L, Kantzanou M, Klenerman P
Abstract excerpt
Understanding the interactions between a host and a pathogen relies crucially on quantitative measurements of immune responses. Until recently, measurements of the levels of cellular immune responses, i.e. those mediated by CD4+ and CD8+ T lymphocytes have depended largely on culture in vitro and subsequent measurement of specific functions (such as cytolysis). More recently, new technologies based around...
Topics
- Animals
- CD8-Positive T-Lymphocytes
- Cytotoxicity, Immunologic
- HIV Infections
- HTLV-I Infections
- Hepatitis B
- Hepatitis C
- Histocompatibility Antigens Class I
- Humans
- Immunity, Cellular
- Lymphocyte Count