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T‐cell activation–induced marker assays in health and disease

24 Feb 2023

Abstract excerpt

Activation-induced marker (AIM) assays have proven to be an accessible and rapid means of antigen-specific T-cell detection. The method typically involves short-term incubation of whole blood or peripheral blood mononuclear cells with antigens of interest, where autologous antigen-presenting cells process and present peptides in complex with major histocompatibility complex (MHC) molecules. Recognition of...

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PMID: 36825901
DOI: 10.1111/imcb.12636

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