Article
G allele of the -930A>G polymorphism of the CYBA gene is associated with insulin resistance in obese subjects.
Journal of physiology and biochemistry - 1 Jun 2008
Ochoa M C, Razquin C, Zalba G, Martínez-González M A, Martínez J A, Marti A
Abstract excerpt
It has been shown that NADPH oxidase plays a role in oxidative stress which has been involved in the development of metabolic syndrome. The -930A/G polymorphism of the CYBA gene (that codes p22phox, a major component of the NADPH oxidase) has been associated with human hypertension and with a reduction in NADPH oxidase activity. In this work, we have examined the influence of the -930A/G polymorphism on obesity...
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