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Article

Estrogen receptor gene polymorphisms in Japanese patients with systemic sclerosis.

Clinical and experimental rheumatology - 1 Jan 2000

Hoshi M, Yasuoka H, Kuwana M

Abstract excerpt

OBJECTIVE: To investigate whether single-nucleotide polymorphisms (SNPs) within the estrogen receptor (ER) alpha and Beta genes are associated with disease susceptibility and clinical presentation in Japanese patients with systemic sclerosis (SSc). METHODS: Three SNPs, ERalpha PvuII T/C, ERalpha XbaI A/G, and ERBeta RsaI G/A, were genotyped using polymerase-chain reaction combined with restriction fragment length...

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PMID: 19032828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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