Article
Sex differences in estrogen receptor gene polymorphism and its association with lupus nephritis in Chinese.
Nephron - 1 Feb 2002
Liu Zhi-Hong, Cheng Zhao-Hong, Gong Ru-Jun, Liu Hao, Liu Dong, Li Lei-Shi
Abstract excerpt
BACKGROUND/AIMS: Lupus nephritis (LN) is a clinical heterogeneous autoimmune disease and genetic factors contribute to the development of LN. One of the most striking characteristics in LN is the high prevalence among childbearing women, as well as that its clinical manifestation differs in women and men, suggesting the role of sex hormones in its pathogenesis. METHODS: The PvuII and XbaI restriction fragment...
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