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Article

Angiotensin II Type 1 receptor (AGTR1) gene polymorphisms are associated with vascular manifestations in patients with systemic sclerosis (SSc).

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jul 2016

Rodríguez-Reyna Tatiana S, Núñez-Alvarez Carlos, Cruz-Lagunas Alfredo, Posadas-Sánchez Rosalinda, Pérez-Hernández Nonanzit, Jiménez-Alvarez Luis, Ramírez-Martínez Gustavo, Granados Julio, Vargas-Alarcón Gilberto, Zúñiga Joaquín

Abstract excerpt

INTRODUCTION: Systemic sclerosis (SSc) shows variable clinical expression in different ethnic groups; vascular abnormalities are a prominent feature of this disease and its clinical expression may be influenced by genetic factors. PATIENTS AND METHODS: Herein, we describe 15 polymorphisms of the renin-angiotensin-aldosterone pathway in 170 Mexican admixed SSc patients (defined as patients with Mexican ancestry...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 27488275
DOI: 10.1177/1470320316659954
PMCID: PMC5843913

Genes

AGTR1
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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